Gut microbes can result in extra weight, says study

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Gut microbes can result in extra weight, says study

Posted: 08/06/2015 07:11 PM IST
Gut microbes can result in extra weight, says study

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The scientists from University of Chicago have found evidence that gut bacteria may affect circadian rhythms and metabolism leading some people to gain extra weight.

They stated that mice with a normal set of gut microbes showed evidence of a regular daily microbial cycle, with different species flourishing in different parts of the day and producing different compounds. These compounds appeared to act on the liver and affected how circadian clock genes were expressed in the liver. Also a high-fat diet reduced the variation in the microbial cycle and the circadian clock genes were disrupted and the mice gained weight.

“The earlier explanation for microbiome-related weight gain was that some bacteria make calories from food more available to your body, but this is a fundamental alternative explanation,” said Jack Gilbert, microbial ecologist at the US Department of Energy’s Argonne National Laboratory.

The study appeared in the journal Cell Host & Microbe.

By Lizitha

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